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Relay Therapeutics shares surge to 52-week high on cancer drug progress

RL stock hits $20.83 intraday, up 496% over one year, as analysts cite Phase 3 breast cancer trial momentum for zovegalisib. Four firms raise targets to $26-$29.

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Priya Anand · Equities & Earnings Desk · 19 Aug 2026 · 08:35 · 1 min read
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Relay Therapeutics shares surge to 52-week high on cancer drug progress

Relay Therapeutics Inc. (RL) shares reached a 52-week high of $20.83 on Tuesday, extending a rally that has pushed the biotech up 496% over the past 12 months. The stock was trading at $20.87 at the time of reporting, valuing the company at approximately $4.52 billion.

Analysts cited progress in the company’s breast cancer treatment pipeline as the primary driver of the advance. Relay’s lead asset, zovegalisib, is being evaluated in multiple clinical trials, including the Phase 3 ReDiscover-2 study, which tests the drug in combination with fulvestrant for metastatic breast cancer. Initial positive results from the Phase 2 ReInspire trial have also contributed to the upbeat outlook.

Coverage updates from major firms reinforced the bullish sentiment. Citizens raised its price target to $26 from $21 and maintained a Market Outperform rating, while Guggenheim reiterated its Buy rating with a $26 target. Canaccord initiated coverage with a Buy rating and a $29 target, citing Relay’s precision oncology approach. JPMorgan also initiated coverage with an Overweight rating and a $28 target, highlighting zovegalisib’s potential across multiple indications.

H.C. Wainwright joined the positive revisions, lifting its price target to $28 from $25 following the ReInspire trial’s early data. The stock’s valuation remains elevated, with InvestingPro analysis indicating it is trading above fair value relative to peers in the sector.

This article was produced with AI assistance and edited by a Finance Review Daily journalist.
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Written by
Priya Anand
Equities & Earnings Desk

Priya covers listed equities and corporate earnings, reading quarterly results and guidance for what they signal about sector health and forward valuations.

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